Inflammatory Arthritis & Connective Tissue Disease for Adult Services, over 16, Transplantation, Immunosuppression, Non rheumatology indications

Inflammatory Arthritis & Connective Tissue Disease for Adult Services

Rationale 1,2,3

"Ciclosporin is a critical-dose drug with a narrow therapeutic index

Care should be taken to stabilise the patient on a single brand of ciclosporin, and to ensure that the same brand of ciclosporin is always prescribed and dispensed to the patient

When switching of a patient stabilised to one brand of ciclosporin is unavoidable, the patient should be closely monitored for side effects, drug blood concentrations, and transplant function.

MHRA Drug Safety Update Volume 3 Issue 5 December 2009"