Prevention of miscarriage
NICE NG126 Ectopic pregnancy and miscarriage: diagnosis and initial management
On 24 November 2021, NICE NG126 published new guidance [1] recommending treatment with progesterone for women with early pregnancy bleeding and at least one previous miscarriage.
The recommendations are very specific:
It is for women who have vaginal bleeding and have previously had at least one miscarriage
They need to have had a scan that shows that here is a pregnancy in the uterus
The treatment is with micronised progesterone[3], 400 mg, twice a day
If a fetal (baby’s) heartbeat is seen on scan, treatment is continued until 16 completed weeks of pregnancy.
The NICE guidance does not recommend progesterone treatment for:
Women who have vaginal bleeding in early pregnancy but have not had a previous miscarriage
Women who have had one or more previous miscarriages but don’t have any vaginal bleeding during early pregnancy.
Guidance provided by Dr Manju Singh
Consultant Obstetrician and Gynaecologist & Clinical Director DBTH ( January 2022)
| Pack | Price |
|---|---|
| 21 capsule | £21.00 |
Indicated for the prevention of miscarriage in women presenting with bleeding in the first trimester of pregnancy and have a history of recurrent miscarriages
Brand Prometrium®
| Pack | Price |
|---|---|
| 15 capsule |
Prevention of preterm birth
NICE NG25 Preterm labour and birth
Prevention of preterm birth in women with a singleton pregnancy who have a short cervix (mid-trimester sonographic cervix ≤25 mm) and/or a history of spontaneous preterm birth
| Pack | Price |
|---|---|
| 21 capsule | £21.00 |
Induction of Labour
Rationale 1
*Hospital use only*
Misoprostol should only be administered by trained obstetric personnel in a hospital setting where facilities for continuous fetal and uterine monitoring is available and the cervix should be assessed carefully before product use.
Uterine atony and postpartum haemorrhage after Caesarean section (prevention of)
Rationale 1,6
Post-partum haemorrhage
Rationale 1,6
| Pack | Price |
|---|---|
| 10 ampoule | £182.01 |
Obstetric uses / Induction of labour
*Hospital use only*
Obstetric uses
Postpartum haemorrhage caused by uterine atony
*Hospital use only*
Rationale 1
Obstetric uses
Obstetric uses
*Hospital use only*