• FCMS
  • Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust
  • Rotherham Doncaster and South Humber NHS Foundation Trust
  • Nottingham and Nottinghamshire
  • South Yorkshire ICB

For information and guidance relating to Denosumab 60mg/mL injection including Shared Care Protocol on the SY MO website  Click here

For information and guidance relating to Ibandronic Acid 50mg tablets as adjuvant therapy in early breast cancer on the SY MO website click here 

Alendronic Acid Tablets

Adrenocortical Function Testing and Antidiuretic Hormone Disorders

(and Other Hormone-Relate Disorders)

Pack Price
4 tablet £0.97

Bisphosphonate

Hypercalcaemia, Paget’s Disease

Pamidronate Disodium Injection 15mg and 30mg Injection 

*Hospital Use Only*

Adjuvant bisphosphonate therapy in breast cancer

Rationale 1

*Hospital Use Only*

 

Bone malignancies and Pagets disease

Rationale 1

*Hospital Use Only*

NICE TA464 Bisphosphonates for treating osteoporosis

NICE NG35 Myeloma: diagnosis and management

 

Bone malignancies and Pagets disease, Treat osteoporosis in men and reduce risk of new fractures following hip fracture

Rationale 1

*Hospital Use Only*

NICE TA464 recommends as treatment for osteoporosis

NICE NG35 Myeloma: diagnosis and management

 

Osteoporosis (prevention) in postmenopausal women at increased risk of fractures

Men with increase risk of fracture

Refer to the Clinical Guideline For Denosumab 60mg/ml Injection

Currently advising to prescribe by brand Stoboclo when available.

MHRA - Drug Safety Update & NHS England Patient Safety alerts May 2022 ‘Denosumab should not be prescribed to anyone under the age of 18 years’

NICE Guidance

Denosumab is Amber for the following indications; 

Denosumab (60mg subcutaneous injection every 6 months) is licensed for the treatment of:
(a) osteoporosis in postmenopausal women and in men at increased risk of fractures due to
osteoporosis
(b) bone loss associated with hormone ablation in men with prostate cancer at increased risk of
fractures
(c) bone loss associated with long term systemic glucocorticoid therapy in patients at increased
risk of fractures

Please note 120mg strength (XGEVA) is RED

Pack Price
1 pre-filled disposable injection £183.00