Prevention of nausea and vomiting associated with highly and moderately emetogenic cancer chemotherapy in adults and adolescents from the age of 12.

Rationale 1,6

Chemotherapy-associated nausea and vomiting

Brand: Ivemend

Rationale: 1

Nausea and vomiting (prevention & treatment of acute) associated with chemotherapy and radiotherapy.

Brand: Mylan

Rationale: 1

Indicated for management of nausea and vomiting induced by chemotherapy or radiotherapy. Treatment to be started an hour before chemotherapy or radiotherapy, then continue for up to one week following chemotherapy or radiotherapy.

Nausea and vomiting (prevention of) associated with moderately or highly emetogenic chemotherapy, for a planned duration of 3 to 5 consecutive days, where oral anti-emetic administration is complicated by factors making swallowing difficult

Brand: SANCUSO

Rationale: 1

Control of nausea and vomiting, caused by chemotherapeutic agents used in the treatment of cancer, in patients who have failed to respond adequately to conventional antiemetic treatments.

Rationale 4

Drug abuse and dependence:
Nabilone is an abusable substance (it is a synthetic cannabinoid), capable of producing subjective side-effects, such as euphoria or "high", at therapeutic doses. Prescriptions should be limited to the amount necessary for a single cycle of chemotherapy (i.e. a few days). The physical dependence capability of Nabilone is unknown. Patients who participated in clinical trials, up to 5 days duration, showed no withdrawal symptoms on cessation of dosing.

SPC Nabilone June 2008

Relief of symptoms associated with neuro endocrine tumours

Brand : Sandostatin + LAR

Rationale 1,2,3

Prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy in adults.

Rationale 1,6