Amiodarone Tablets

Arrythmias - ventricular and supraventricular

Brand : Cordarone X

Refer to Shared Care Protocol

NICE CG 180 The Management of AF

Amiodarone (Cordarone X): reminder of risks of treatment and need for patient monitoring and supervision
Amiodarone has been associated with serious and potentially life-threatening side effects, particularly of the lung, liver, and thyroid gland.
We remind healthcare professionals that patients should be supervised and reviewed regularly during treatment. Lung problems may have slow onset but then progress rapidly. Computerised tomography scans may help to confirm a suspected diagnosis of pulmonary toxicity.

MHRA Drug Safety Update Avoid concomitant use of amiodarone with simeprevir (Olysio) and sofosbuvir (Sovaldi) combination therapy, unless other antiarrhythmics cannot be given.

Review Date: 01/11/2026

Propafenone Tablets

Prophylaxis of and ventricular arrhythmias

Brand: Arythmol

It is recommended that Propafenone therapy should be initiated under hospital conditions, by a physician experienced in the treatment of arrhythmias. The individual maintenance dose should be determined under cardiological surveillance including ECG monitoring and blood pressure control.