Oedema in congestive heart failure, oedema in renal disease and hypertension.

Xaqua - To be prescribed by brand - Please specify when prescribing

Please see Guidance document at the top of this section

The Summary of Product Characteristics for the UK-licensed metolazone tablets Xaqua state that there is up to a two-fold difference in bioavailability compared to other (unlicensed, imported) metolazone preparations. A dose adjustment may be necessary and individualised titration based on patient’s response and tolerability is advised if switching from Xaqua tablets to another metolazone product, or vice versa.