Digoxin Tablets and Oral Solution
Control of ventricular rate (>100 beats per minute) in patients with atrial fibrillation and atrial flutter and is also used in some heart failure patients.
Equivalence of Digoxin Preparations:
The bioavailability of digoxin preparations is not identical. Care should be taken when converting between preparations.
Bioavailability of IV preparation = 1
Bioavailability of liquid = 0.8
Bioavailability of tablets = 0.63
As a general rule: 62.5micrograms (tablet) ≡ 50micrograms (liquid) ≡ 40micrograms (injection)
| Pack | Price |
|---|---|
| 28 tablet | £1.02 |
| Pack | Price |
|---|---|
| 28 tablet | £1.06 |
| Pack | Price |
|---|---|
| 60 ml | £6.95 |
| Pack | Price |
|---|---|
| 28 tablet | £1.03 |
*Hospital Use Only*
Equivalence of Digoxin Preparations:
The bioavailability of digoxin preparations is not identical. Care should be taken when converting between preparations.
Bioavailability of IV preparation = 1
Bioavailability of liquid = 0.8
Bioavailability of tablets = 0.63
As a general rule: 62.5micrograms (tablet) ≡ 50micrograms (liquid) ≡ 40micrograms (injection)
For the Treatment of Life-Threatening Digoxin Toxicity
Prescribing Guidance
Digifab is indicated for the treatment of life-threatening digoxin toxicity
associated with ventricular arrhythmias or Brady arrhythmias unresponsive to
atropine where measures beyond withdrawal of digoxin and correction of
serum electrolyte abnormalities are considered necessary.
Prescribing information can be obtained via the National Poisons Information
Service (NPIS) on 08448920111 (there is also a summary of prescribing
information via the NPIS website; username and password required) or from
medicines information via DRI extension 644325
Rationale 1,6
| Pack | Price |
|---|---|
| 1 vial | £750.00 |